Department of Physiology, University of Oslo

Current research focus

Myocardial protection against acute ischemic injury and development of postinfarction heart failure

Research projects

Project manager

• Water channals in the heart

Supervisor

• Gender and cardiovascular disease
• Mitochondrial DNA - maker or marker of ischemic injury?
• The role of fetal gene programs for development of acute infarction and postischemic heart failure
• A role of retinoic acid in remodelling of the failing heart
• Glutamate transporters in the hearts of rats and mice
• Is heme oxygenase-1 a downstream mediator of HIF-1a induced protection?
• Mitochondrial p66Shc - friend or foe?
• Role of CCN2/CTGF in in autonomic control of the heart
• DNA repair enzymes in ischemia-reperfusion injury
• Innate immunity and cardiac injury

Collaborator

• Characterization of intracellular signaling pathways of CTGF and mechanisms of cytoprotective actions in cardiac myocytes
• Mechanisms of cardioprotection
• Identification of factors that stimulate survival and proliferation of cardiac progenitor cells.
• Identification and characterization of factors that stimulate proliferation and survival of cardiac stem cells
• Role of the innate immun system in the development and maintenance of cardiovascular disease