Institute for Experimental Medical Research, Oslo University Hospital Ullevaal and Department of Cardiothoracic Surgery, Oslo University Hospital Ullevaal

Current research focus

Mechanisms of heart failure, cytokine expression and their role in myocardial remodelling

Research projects

Supervisor

• Mechanisms regulating reverse remodeling after relief of pressure overload of the left ventricle
• Phosphorylation of SMAD2 regulates myocardial remodeling following pressure overload
• New aspects in myocardial remodeling and dysfunction due to left ventricular pressure overload
• The role of collagen type VIII during reverse myocardial remodeling

Collaborator

• Targeting of Na⁺ transporting proteins determines cardiac contractility and rhythm
• Expression of embryonic gene programs in heart failure and acute ischemia
• Mechanisms regulating left ventricular remodelling in patients with aortic stenosis.