Institute for Experimental Medical Research, Oslo University Hospital Ullevaal

Current research focus

Basic mechanisms for triggered arrhythmias

Research projects

Project manager

• Determining factors for triggered arrhythmias
• L-type Ca2+ current inhibition for prevention of triggered arrhythmias
• Exercise training as anti-arrhythmic therapy in heart failure

Supervisor

• Can excercise training prevent triggered ventricular arrhythmias in patients?
• Can exercise training prevent arrhythmogenic SR Ca2+ leak in mice?
• Causal link between contractile dysfunction and risk of arrhythmias in post infarction rats
• Can exercise training prevent ventricular arrhythmias in heart failure?

Collaborator

• Crosstalk between transport proteins that control intracellular sodium in cardiomyoctyes
• IP₃ signalling and Ca²⁺-wave development in ventricular cardiomyocytes
• Spatial homogeneity of cardiomyocyte Ca²⁺ handling and sarcomeric function
• Optimization of gene deletion protocols in mouse models utilizing Mer-Cre-Mer (MCM) technology