Department of Pharmacology, University of Oslo

Current research focus

Study the effects of natriuretic peptides on negative inotropy and the signalling mechanisms involved.

Research projects

Project manager

• Regulation of serotonin receptor expression in normal and failing hearts
• Mechanism of action of 5-HT₄ serotonin receptors in failing myocardium
• Signalling mechanisms for the negative inotropic effect of natriuretic peptides in failing myocardium

Collaborator

• Crosstalk of cGMP on cAMP signalling systems in cardiomyocytes. A key to modifications of cAMP-dependent receptor functions in failing myocardium?
• Regulation of myocardial cGMP by PDE subtypes.