23016831
w.e.louch
medisin.uio.no
Institute for Experimental Medical Research, Oslo University Hospital Ullevaal
Current research focus
Control of ions and metabolism in skeletal muscle especially in relation to excitation-contraction coupling
Research projects
Project manager
Supervisor
- Mechanisms underlying the force-frequency response in normal and failing cardiomyocytes
- Spatial homogeneity of cardiomyocyte Ca2+ handling and sarcomeric function
Collaborator
- Electrical remodelling in heart failure
- The role of SERCA2 in calcium dependent arrhythmias
- Heart failure protein interaction
- Serca2 function in the embryonic heart
- Crosstalk between transport proteins that control intracellular sodium in cardiomyoctyes
- Identification and modulation of signaling complexes involved in hypertrophy and heart failure
- Secretoneurin in cardiac ischemia and heart failure
- The homeostatic chemokine CXCL13 and its receptor CXCR5 are regulated in experimental and human heart failure, and are involved in cardiac remodelling.
- Molecular processes triggered by altered Ca2+ cycling and SR dysfunction in heart failure
- Chromogranin A, granins and heart disease
- Effect of beta-adrenergic stimulation on Ca2+ wave development in SERCA2 KO mice
- L-type Ca2+ channel antagonism for Ca2+-triggered arrhythmias: Novel treatment strategy or potentially harmfull?
- Optimization of gene deletion protocols in mouse models utilizing Mer-Cre-Mer (MCM) technology
- Role of Neil3 in regulating stem cell recruitment following myocardial infarction