Department of Cardiology, Oslo University Hospital Rikshospitalet

Current research focus

The aim of our research is to improve diagnostics and treatment of cardiovascular diseases and to increase knowledge about myocardial function. The research activities include cardiovascular imaging by echocardiography, MR and CT and how to best combine more than one imaging modality. Another important research area is development of new diagnostic tools. Clinical problem settings are tested in experimental models and the translation aspect involves close cooperation with the Institute for Surgical Research and the Interventional Centre at Rikshospitalet University Hospital.

Research projects

Supervisor

• Cardic mechanics in LV dyssynchrony
• LV function and ventricular arrhythmias
• Adaptive servoventilation and LV function
• Characterization of intracellular signaling pathways of CTGF and mechanisms of cytoprotective actions in cardiac myocytes
• Left ventricular function and risk of arrhythmia in patients with cardiomyopathies. A strain echocardiographic study.

Collaborator

• Significance of pulmonary monocyte/macrophage system in the pathophysiologic mechanisms of heart failure
• Involvement of GRK3 in the pathophysiologic mechanisms of heart failure
• Mechanisms of elevated plasma endothelin-1 levels in heart failure
• Functional significance of CTGF-induced restrictive fibrosis of the heart in endurance training vs. heart failure
• Role of myocardial CTGF in the pathophysiologic mechanisms of heart failure
• Exercise training as anti-arrhythmic therapy in heart failure