Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 (GRK3) in mice does not alter the hypertrophic response, but attenuates cardiac dysfunction after chronic pressure overload.
Prostanoids mediate a sustained positive inotropic response in non-failing human and rat ventricular myocardium and this response appears to be down-regulated in failing hearts.
Patients with heart failure of ischemic etiology included in the CORONA trial with galectin-3 values <19.0 ng/mL had a lower primary event rate (cardiovascular death, myocardial infarction, or stroke), lower total mortality, and lower event rate of all-cause mortality and HF hospitalizations after rosuvastatin treatment compared with placebo.
The 10th Annual CHFR Symposium will take place on September 20-21, 2012.
Abstract deadline: June 1, 2012
Registration deadline: August 10, 2012
Read about our education program here
Read abstracts from our publications here
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