Hot Topics:Agents increasing cGMP amplify 5-HT(4)-elicited positive inotropic response in failing hearts

Cyclic GMP from different sources is functionally compartmented, giving differential regulation of different G(s)-coupled receptors in failing myocardium.
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Hot Topics: Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload

In pressure overload in mice, inhibition of SMAD2 signaling prevents downregulation of SERCA2 and attenuates cardiomyocyte hypertrophy and preserves cardiac function.
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Hot Topics: Possible link between disturbed fatty acid composition and the progression of heart failure

In patients with heart failure, low circulating levels of eicosatetraenoic acid and high levels of vaccenic acid are associated with disease severity and mortality.
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10th Annual CHFR Symposium

The 10th Annual CHFR Symposium will take place on September 20-21, 2012.
Mark your calendars!

Abstract deadline: June 1, 2012
Registration deadline: August 10, 2012